3i58 | pdb_00003i58

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Template:STRUCTURE 3i58

File:3i58.jpg

Crystal structure of an O-methyltransferase (NcsB1) from neocarzinostatin biosynthesis in complex with S-adenosyl-L-homocysteine (SAH) and 2-hydroxy-7-methoxy-5-methyl naphthoic acid (NA)

Template:ABSTRACT PUBMED 19702337

About this Structure

3I58 is a 2 chains structure of sequences from Streptomyces carzinostaticus subsp. neocarzinostaticus. Full crystallographic information is available from OCA.

Reference

  1. Cooke HA, Guenther EL, Luo Y, Shen B, Bruner SD. Molecular basis of substrate promiscuity for the SAM-dependent O-methyltransferase NcsB1, involved in the biosynthesis of the enediyne antitumor antibiotic neocarzinostatin. Biochemistry. 2009 Aug 25. PMID:19702337 doi:10.1021/bi901257q

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