3g6w | pdb_00003g6w

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Template:STRUCTURE 3g6w

File:3g6w.jpg

Asymetric GTP bound structure of UPRTase from Sulfolobus solfataricus containing PRPP-mg2+ in half of the active sites and R5P and PPi in the other half

Template:ABSTRACT PUBMED 19683539

About this Structure

3G6W is a 4 chains structure of sequences from Sulfolobus solfataricus. Full crystallographic information is available from OCA.

Reference

  1. Christoffersen S, Kadziola A, Johansson E, Rasmussen M, Willemoes M, Jensen KF. Structural and kinetic studies of the allosteric transition in Sulfolobus solfataricus uracil phosphoribosyltransferase: Permanent activation by engineering of the C-terminus. J Mol Biol. 2009 Oct 23;393(2):464-77. Epub 2009 Aug 14. PMID:19683539 doi:10.1016/j.jmb.2009.08.019
  2. Arent S, Harris P, Jensen KF, Larsen S. Allosteric regulation and communication between subunits in uracil phosphoribosyltransferase from Sulfolobus solfataricus. Biochemistry. 2005 Jan 25;44(3):883-92. PMID:15654744 doi:10.1021/bi048041l

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