2np8 | pdb_00002np8

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File:2np8.png

Template:STRUCTURE 2np8

Structural Basis for the Inhibition of Aurora A Kinase by a Novel Class of High Affinity Disubstituted Pyrimidine Inhibitors

Template:ABSTRACT PUBMED 17157005

Disease

Known disease associated with this structure: Colon cancer, susceptibility to OMIM:[603072]

About this Structure

2NP8 is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Tari LW, Hoffman ID, Bensen DC, Hunter MJ, Nix J, Nelson KJ, McRee DE, Swanson RV. Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitors. Bioorg Med Chem Lett. 2007 Feb 1;17(3):688-91. Epub 2006 Nov 2. PMID:17157005 doi:https://dx.doi.org/10.1016/j.bmcl.2006.10.086

Page seeded by OCA on Thu Sep 3 16:25:29 2009

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OCA

[1] Tari LW, Hoffman ID, Bensen DC, Hunter MJ, Nix J, Nelson KJ, McRee DE, Swanson RV. Structural basis for the inhibition of Aurora A kinase by a novel class of high affinity disubstituted pyrimidine inhibitors. Bioorg Med Chem Lett. 2007 Feb 1;17(3):688-91. Epub 2006 Nov 2. PMID:17157005 doi:https://dx.doi.org/10.1016/j.bmcl.2006.10.086

2np8 | pdb_00002np8

Contents

Structural Basis for the Inhibition of Aurora A Kinase by a Novel Class of High Affinity Disubstituted Pyrimidine Inhibitors

Disease

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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