3gpw | pdb_00003gpw
From Proteopedia
Crystal structure of the yeast 20S proteasome in complex with Salinosporamide derivatives: irreversible inhibitor ligand
About this Structure
3GPW is a 28 chains structure of sequences from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
Reference
- Groll M, McArthur KA, Macherla VR, Manam RR, Potts BC. Snapshots of the fluorosalinosporamide/20S complex offer mechanistic insights for fine tuning proteasome inhibition. J Med Chem. 2009 Sep 10;52(17):5420-8. PMID:19678642 doi:10.1021/jm900559x
Page seeded by OCA on Wed Sep 16 09:02:11 2009
Proteopedia Page Contributors and Editors (what is this?)
Categories:
- Pages with broken file links
- Proteasome endopeptidase complex
- Saccharomyces cerevisiae
- Arthur, K A.M.
- Groll, M.
- Macherla, V R.
- Manam, R R.
- Potts, C B.
- Cancer therapy
- Cytoplasm
- Hydrolase
- Immunology
- Isopeptide bond
- Nucleus
- Phosphoprotein
- Protease
- Proteasome
- Threonine protease
- Time-dependent elimination of a defined leaving group
- Ubiquitin
- Ubl conjugation
- Zymogen
