MDM2

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Template:STRUCTURE 1ycq

MDM2 BOUND TO HUMAN P53 Protein

Template:ABSTRACT PUBMED 8875929

About this Structure

1YCQ is a 2 chains structure of sequences from Xenopus laevis. The July 2002 RCSB PDB Molecule of the Month feature on p53 Tumor Suppressor by David S. Goodsell is 10.2210/rcsb_pdb/mom_2002_7. Full crystallographic information is available from OCA.

Reference

  1. Kussie PH, Gorina S, Marechal V, Elenbaas B, Moreau J, Levine AJ, Pavletich NP. Structure of the MDM2 oncoprotein bound to the p53 tumor suppressor transactivation domain. Science. 1996 Nov 8;274(5289):948-53. PMID:8875929