3eig | pdb_00003eig

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Template:STRUCTURE 3eig

File:3eig.png

Crystal structure of a methotrexate-resistant mutant of human dihydrofolate reductase

Template:ABSTRACT PUBMED 19478082

About this Structure

3EIG is a 1 chain structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Volpato JP, Yachnin BJ, Blanchet J, Guerrero V, Poulin L, Fossati E, Berghuis AM, Pelletier JN. Multiple conformers in active site of human dihydrofolate reductase F31R/Q35E double mutant suggest structural basis for methotrexate resistance. J Biol Chem. 2009 Jul 24;284(30):20079-89. Epub 2009 May 28. PMID:19478082 doi:10.1074/jbc.M109.018010

Page seeded by OCA on Mon Sep 21 20:13:36 2009

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OCA

[1] Volpato JP, Yachnin BJ, Blanchet J, Guerrero V, Poulin L, Fossati E, Berghuis AM, Pelletier JN. Multiple conformers in active site of human dihydrofolate reductase F31R/Q35E double mutant suggest structural basis for methotrexate resistance. J Biol Chem. 2009 Jul 24;284(30):20079-89. Epub 2009 May 28. PMID:19478082 doi:10.1074/jbc.M109.018010

3eig | pdb_00003eig

Crystal structure of a methotrexate-resistant mutant of human dihydrofolate reductase

About this Structure

Reference

Proteopedia Page Contributors and Editors (what is this?)

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