13er
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Cryo-EM structure of HAdV-C6 hexon trimer in complex with prothrombin (FII)
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Structural highlights
FunctionB2ZWX4_ADE06 Major capsid protein that self-associates to form 240 hexon trimers, each in the shape of a hexagon, building most of the pseudo T=25 capsid. Assembled into trimeric units with the help of the chaperone shutoff protein. Transported by pre-protein VI to the nucleus where it associates with other structural proteins to form an empty capsid. Might be involved, through its interaction with host dyneins, in the intracellular microtubule-dependent transport of incoming viral capsid to the nucleus.[ARBA:ARBA00024662][HAMAP-Rule:MF_04051] Contents | ||||||||||||||||||||
This page was last modified 07:16, 8 July 2026.