1nu0 is a 2 chain structure with sequence from Escherichia coli. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
YQGF_ECOLI Involved in the processing of the 5'-end of pre-16S rRNA during 70S ribosome maturation (processing does not occur on total cellular RNA off the ribosome); may be a nuclease (PubMed:25545592). A temperature-sensitive yqgF mutant no longer grows when Rho or NusA are overproduced, and has reduced transcription of genes encoded downstream of Rho terminators; transcription increases again in the presence of the Rho inhibitor bicylomycin (PubMed:22353788).[1][2]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
↑Iwamoto A, Osawa A, Kawai M, Honda H, Yoshida S, Furuya N, Kato J. Mutations in the essential Escherichia coli gene, yqgF, and their effects on transcription. J Mol Microbiol Biotechnol. 2012;22(1):17-23. PMID:22353788 doi:10.1159/000336517
↑Kurata T, Nakanishi S, Hashimoto M, Taoka M, Yamazaki Y, Isobe T, Kato JI. Novel essential gene Involved in 16S rRNA processing in Escherichia coli. J Mol Biol. 2015 Feb 27;427(4):955-965. PMID:25545592 doi:10.1016/j.jmb.2014.12.013
