3run

New strategy to analyze structures of glycopeptide antibiotic-target complexes

spinqualitylabelsall models 3run, resolution 1.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 3run is a 2 chain structure with sequence from Amycolatopsis orientalis and Escherichia virus T4. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.4Å Ligands: 3FG, BGC, CCS, CL, DAL, GHP, IPA, MLU, MPD, MRD, OMY, OMZ, PO4, PRD_000204, RER, TRS Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function ENLYS_BPT4 Endolysin with lysozyme activity that degrades host peptidoglycans and participates with the holin and spanin proteins in the sequential events which lead to the programmed host cell lysis releasing the mature viral particles. Once the holin has permeabilized the host cell membrane, the endolysin can reach the periplasm and break down the peptidoglycan layer. See Also Lysozyme 3D structures

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