4e86

Crystal structure of human alpha-defensin 5, HD5 (Leu29Aba mutant)

spinqualitylabelsall models 4e86, resolution 2.75Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 4e86 is a 9 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.75Å Ligands: ABA, CL Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function DEF5_HUMAN Has antimicrobial activity against Gram-negative and Gram-positive bacteria. Defensins are thought to kill microbes by permeabilizing their plasma membrane. All DEFA5 peptides exert antimicrobial activities, but their potency is affected by peptide processing. See Also Defensin 3D structures

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