6kdr | pdb_00006kdr
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Crystal structure of human NRMT2 in complex with human centromere protein B peptide
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Structural highlights
FunctionNTM1B_HUMAN Alpha-N-methyltransferase that methylates the N-terminus of target proteins containing the N-terminal motif [Ala/Pro/Ser]-Pro-Lys when the initiator Met is cleaved. Specifically catalyzes monomethylation of exposed alpha-amino group of Ala or Ser residue in the [Ala/Ser]-Pro-Lys motif and Pro in the Pro-Pro-Lys motif. May activate NTMT1 by priming its substrates for trimethylation.[1] References
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This page was last modified 10:31, 22 November 2023.