6kjf

lovastatin esterase PcEST in complex with simvastatin

spinqualitylabelsall models 6kjf, resolution 2.40Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6kjf is a 2 chain structure with sequence from Penicillium rubens Wisconsin 54-1255. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.4Å Ligands: 144, SIM Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function PCEST_PENRW Esterase that can hydrolyze the side chain of lovastatin to produce monacolin J (PubMed:28619444, PubMed:31839596). Is also able to hydrolyze the side chains of mevastatin and pravastatin, but not simvastatin (PubMed:28619444).

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