6m8o | pdb_00006m8o

Crystal structure of the receiver domain of LytR from Staphylococcus aureus

spinqualitylabelsall models 6m8o, resolution 2.50Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6m8o is a 1 chain structure with sequence from Staphylococcus aureus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.5Å Ligands: SO4 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function LYTR_STAA8 Member of the two-component regulatory system LytR/LytS that regulates genes involved in autolysis, programmed cell death, biofilm formation and cell wall metabolism (PubMed:19502411). Participates also in sensing and responding to host defense cationic antimicrobial peptides (HDPs) (PubMed:23733465). Upon phosphorylation by LytS, functions as a transcription regulator by direct binding to promoter regions of target genes including lrgA and lrgB, to positively regulate their expression (PubMed:8824633, PubMed:25491472). See Also Response regulator 3D structure

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