6z5s

RC-LH1(14)-W complex from Rhodopseudomonas palustris

spinqualitylabelsall models 6z5s, resolution 2.65Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 6z5s is a 32 chain structure with sequence from Rhodopseudomonas palustris CGA009. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Electron Microscopy, Resolution 2.65Å Ligands: 6PL, BPH, CDL, CRT, FE, FME, LMT, PGT, QAK, U10 Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function Q6N1K3_RHOPA Publication Abstract from PubMed The reaction-center light-harvesting complex 1 (RC-LH1) is the core photosynthetic component in purple phototrophic bacteria. We present two cryo-electron microscopy structures of RC-LH1 complexes from Rhodopseudomonas palustris A 2.65-A resolution structure of the RC-LH1(14)-W complex consists of an open 14-subunit LH1 ring surrounding the RC interrupted by protein-W, whereas the complex without protein-W at 2.80-A resolution comprises an RC completely encircled by a closed, 16-subunit LH1 ring. Comparison of these structures provides insights into quinone dynamics within RC-LH1 complexes, including a previously unidentified conformational change upon quinone binding at the RC Q(B) site, and the locations of accessory quinone binding sites that aid their delivery to the RC. The structurally unique protein-W prevents LH1 ring closure, creating a channel for accelerated quinone/quinol exchange. Structures of Rhodopseudomonas palustris RC-LH1 complexes with open or closed quinone channels.,Swainsbury DJK, Qian P, Jackson PJ, Faries KM, Niedzwiedzki DM, Martin EC, Farmer DA, Malone LA, Thompson RF, Ranson NA, Canniffe DP, Dickman MJ, Holten D, Kirmaier C, Hitchcock A, Hunter CN Sci Adv. 2021 Jan 13;7(3):eabe2631. doi: 10.1126/sciadv.abe2631. Print 2021 Jan. PMID:33523887 From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.

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