7k72

Structure of DNA ligase A from Mycobacterium tuberculosis bound to NAD

spinqualitylabelsall models 7k72, resolution 2.05Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7k72 is a 4 chain structure with sequence from Mycobacterium tuberculosis H37Rv. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.05Å Ligands: CA, MG, MPD, NAD Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function DNLJ_MYCTU DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double-stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.[HAMAP-Rule:MF_01588] See Also DNA ligase 3D structures

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