7p71

The PDZ domain of MAGI1_2 complexed with the PDZ-binding motif of HPV35-E6

spinqualitylabelsall models 7p71, resolution 2.60Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 7p71 is a 4 chain structure with sequence from Homo sapiens and Human papillomavirus 35. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 2.6Å Ligands: CA, CIT, GOL Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function MAGI1_HUMAN May play a role as scaffolding protein at cell-cell junctions. May regulate acid-induced ASIC3 currents by modulating its expression at the cell surface (By similarity).ANXA2_HUMAN Calcium-regulated membrane-binding protein whose affinity for calcium is greatly enhanced by anionic phospholipids. It binds two calcium ions with high affinity. May be involved in heat-stress response.

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