8ayf

Crystal structure of human Sphingosine-1-phosphate lyase 1

spinqualitylabelsall models 8ayf, resolution 1.84Å Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8ayf is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: X-ray diffraction, Resolution 1.84Å Ligands: ACT, GOL, LLP Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function SGPL1_HUMAN Cleaves phosphorylated sphingoid bases (PSBs), such as sphingosine-1-phosphate, into fatty aldehydes and phosphoethanolamine. Elevates stress-induced ceramide production and apoptosis.

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