8ef4 | pdb_00008ef4

Solution structural bundle of bivalirudin - a bivalent hirudin based thrombin inhibitor

spinqualitylabelsall models 8ef4 Show:Asymmetric Unit Biological Assembly Drag the structure with the mouse to rotate   Export Animated Image   Print3D Structural highlights 8ef4 is a 1 chain structure with sequence from Hirudo medicinalis. Full experimental information is available from OCA. For a guided tour on the structure components use FirstGlance. Method: Solution NMR, models Ligands: DPN Resources: FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT Function HIRV2_HIRME Hirudin is a potent thrombin-specific protease inhibitor. It forms a stable non-covalent complex with alpha-thrombin, thereby abolishing its ability to cleave fibrinogen.

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