8qzv | pdb_00008qzv
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Crystal structure of translation factor eIF5A from Trichomonas vaginalis
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Structural highlights
FunctionD5MC19_TRIVA Translation factor that promotes translation elongation and termination, particularly upon ribosome stalling at specific amino acid sequence contexts. Binds between the exit (E) and peptidyl (P) site of the ribosome and promotes rescue of stalled ribosome: specifically required for efficient translation of polyproline-containing peptides as well as other motifs that stall the ribosome. Acts as ribosome quality control (RQC) cofactor by joining the RQC complex to facilitate peptidyl transfer during CAT tailing step.[RuleBase:RU362005] Contents | ||||||||||||||||||
This page was last modified 07:17, 3 July 2024.