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Cryo-EM Structure of the Glycosyltransferase ArnC from Salmonella enterica in the Apo State Determined on Talos Arctica microscope
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Structural highlights
FunctionARNC_SALTY Catalyzes the transfer of 4-deoxy-4-formamido-L-arabinose from UDP to undecaprenyl phosphate. The modified arabinose is attached to lipid A and is required for resistance to polymyxin and cationic antimicrobial peptides. Plays an important role in pathogenesis by providing resistance to antimicrobial peptides within macrophages or at other anatomic sites encountered during infection.[1] References
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This page was last modified 06:22, 5 February 2025.