Structural highlights
Function
HAL3A_ARATH Involved in plant growth and salt and osmotic tolerance. Catalyzes the decarboxylation of 4'-phosphopantothenoylcysteine to 4'-phosphopantetheine, a key step in coenzyme A biosynthesis. The enzyme is also able to decarboxylate pantothenoylcysteine to pantothenoylcysteamine.[1] [2]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Kupke T, Hernandez-Acosta P, Culianez-Macia FA. 4'-phosphopantetheine and coenzyme A biosynthesis in plants. J Biol Chem. 2003 Oct 3;278(40):38229-37. Epub 2003 Jul 14. PMID:12860978 doi:http://dx.doi.org/10.1074/jbc.M306321200
- ↑ Rubio S, Larson TR, Gonzalez-Guzman M, Alejandro S, Graham IA, Serrano R, Rodriguez PL. An Arabidopsis mutant impaired in coenzyme A biosynthesis is sugar dependent for seedling establishment. Plant Physiol. 2006 Mar;140(3):830-43. Epub 2006 Jan 13. PMID:16415216 doi:http://dx.doi.org/10.1104/pp.105.072066