Structural highlights
Function
CNOT4_HUMAN Has E3 ubiquitin ligase activity. The CCR4-NOT complex functions as general transcription regulation complex.[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Albert TK, Hanzawa H, Legtenberg YI, de Ruwe MJ, van den Heuvel FA, Collart MA, Boelens R, Timmers HT. Identification of a ubiquitin-protein ligase subunit within the CCR4-NOT transcription repressor complex. EMBO J. 2002 Feb 1;21(3):355-64. PMID:11823428 doi:http://dx.doi.org/10.1093/emboj/21.3.355