1h6i

From Proteopedia

A REFINED STRUCTURE OF HUMAN AQUAPORIN 1

Structural highlights

1h6i is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	Electron crystallography, Resolution 3.54Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

AQP1_HUMAN Forms a water-specific channel that provides the plasma membranes of red cells and kidney proximal tubules with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.^[1]

Evolutionary Conservation

Checkto colour the structure by Evolutionary Conservation, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

References

↑ Preston GM, Carroll TP, Guggino WB, Agre P. Appearance of water channels in Xenopus oocytes expressing red cell CHIP28 protein. Science. 1992 Apr 17;256(5055):385-7. PMID:1373524

1 Structural highlights
2 Function
3 Evolutionary Conservation
4 See Also
5 References

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PDB ID 1h6i

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Categories: Homo sapiens | Large Structures | De Groot BL | Engel A | Grubmuller H

1h6i

From Proteopedia

A REFINED STRUCTURE OF HUMAN AQUAPORIN 1

Structural highlights

Function

Evolutionary Conservation

See Also

References

Contents

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