1pbk

From Proteopedia

HOMOLOGOUS DOMAIN OF HUMAN FKBP25

Structural highlights

1pbk is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 2.5Å
Ligands:	RAP
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FKBP3_HUMAN FK506- and rapamycin-binding proteins (FKBPs) constitute a family of receptors for the two immunosuppressants which inhibit T-cell proliferation by arresting two distinct cytoplasmic signal transmission pathways. PPIases accelerate the folding of proteins.

Evolutionary Conservation

Checkto colour the structure by Evolutionary Conservation, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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PDB ID 1pbk

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1pbk

From Proteopedia

HOMOLOGOUS DOMAIN OF HUMAN FKBP25

Structural highlights

Function

Evolutionary Conservation

See Also

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