2wiw

From Proteopedia

Jump to: navigation, search

Crystal structures of Holliday junction resolvases from Archaeoglobus fulgidus bound to DNA substrate

Structural highlights

2wiw is a 4 chain structure with sequence from Archaeoglobus fulgidus and Synthetic construct. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.8Å
Ligands:GOL, HEZ
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

HJC_ARCFU A structure-specific endonuclease that resolves Holliday junction (HJ) intermediates during genetic recombination. Cleaves 4-way DNA junctions introducing paired nicks in opposing strands, leaving a 5'-terminal phosphate and a 3'-terminal hydroxyl group that are ligated to produce recombinant products.[HAMAP-Rule:MF_01490]

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

Contents


PDB ID 2wiw

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://proteopedia.org/wiki/index.php/2wiw"
Personal tools