Structural highlights
Function
[NAV2_HUMAN] Possesses 3' to 5' helicase activity and exonuclease activity. Involved in neuronal development, specifically in the development of different sensory organs.[1] [2]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Ishiguro H, Shimokawa T, Tsunoda T, Tanaka T, Fujii Y, Nakamura Y, Furukawa Y. Isolation of HELAD1, a novel human helicase gene up-regulated in colorectal carcinomas. Oncogene. 2002 Sep 12;21(41):6387-94. PMID:12214280 doi:http://dx.doi.org/10.1038/sj.onc.1205751
- ↑ Peeters PJ, Baker A, Goris I, Daneels G, Verhasselt P, Luyten WH, Geysen JJ, Kass SU, Moechars DW. Sensory deficits in mice hypomorphic for a mammalian homologue of unc-53. Brain Res Dev Brain Res. 2004 Jun 21;150(2):89-101. PMID:15158073 doi:http://dx.doi.org/10.1016/j.devbrainres.2004.03.004