3akm

From Proteopedia

Jump to: navigation, search

X-ray structure of iFABP from human and rat with bound fluorescent fatty acid analogue

Structural highlights

3akm is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:11D, MG
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

FABPI_HUMAN FABP are thought to play a role in the intracellular transport of long-chain fatty acids and their acyl-CoA esters. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis. Binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 may also help maintain energy homeostasis by functioning as a lipid sensor.

See Also

Contents


PDB ID 3akm

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://proteopedia.org/wiki/index.php/3akm"
Personal tools