3hkv

Structural highlights

Function

PAR10_HUMAN May play a role in cell proliferation. May be required for the maintenance of cell cycle progression.^{[1] [2]}

Evolutionary Conservation

Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

See Also

• Poly(ADP-ribose) polymerase 3D structures

References

1. ↑ Yu M, Schreek S, Cerni C, Schamberger C, Lesniewicz K, Poreba E, Vervoorts J, Walsemann G, Grotzinger J, Kremmer E, Mehraein Y, Mertsching J, Kraft R, Austen M, Luscher-Firzlaff J, Luscher B. PARP-10, a novel Myc-interacting protein with poly(ADP-ribose) polymerase activity, inhibits transformation. Oncogene. 2005 Mar 17;24(12):1982-93. PMID:15674325 doi:http://dx.doi.org/1208410
2. ↑ Chou HY, Chou HT, Lee SC. CDK-dependent activation of poly(ADP-ribose) polymerase member 10 (PARP10). J Biol Chem. 2006 Jun 2;281(22):15201-7. Epub 2006 Feb 2. PMID:16455663 doi:http://dx.doi.org/10.1074/jbc.M506745200