3hxf

From Proteopedia

Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 32)

Structural highlights

3hxf is a 2 chain structure with sequence from Rattus norvegicus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.9Å
Ligands:	BD9, CA, ZN
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PGTA_RAT Catalyzes the transfer of a geranyl-geranyl moiety from geranyl-geranyl pyrophosphate to both cysteines in Rab proteins with an -XXCC, -XCXC and -CCXX C-terminal, such as RAB1A, RAB3A and RAB5A respectively.

Evolutionary Conservation

Checkto colour the structure by Evolutionary Conservation, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.

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PDB ID 3hxf

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3hxf

From Proteopedia

Engineered RabGGTase in complex with a peptidomimetic inhibitor (compound 32)

Structural highlights

Function

Evolutionary Conservation

See Also

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