Structural highlights
Function
CCR_STRCU May play a role in supplying butyryl-CoA for straight-chain fatty acid biosynthesis. Catalyzes the conversion of crotonyl-CoA to butyryl-CoA. It shows a high substrate specificity for crotonyl-CoA, a short-chain-length (C4), but no measurable activity is observed with shorter (C3) or longer-chain-length enoyl-CoA thioesters.[1]
Evolutionary Conservation
Check, as determined by ConSurfDB. You may read the explanation of the method and the full data available from ConSurf.
References
- ↑ Wallace KK, Bao ZY, Dai H, Digate R, Schuler G, Speedie MK, Reynolds KA. Purification of crotonyl-CoA reductase from Streptomyces collinus and cloning, sequencing and expression of the corresponding gene in Escherichia coli. Eur J Biochem. 1995 Nov 1;233(3):954-62. PMID:8521864 doi:10.1111/j.1432-1033.1995.954_3.x
