3l7u
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proteopedia linkproteopedia linkCrystal structure of human NM23-H1
Structural highlights
FunctionNDKA_HUMAN Major role in the synthesis of nucleoside triphosphates other than ATP. Possesses nucleoside-diphosphate kinase, serine/threonine-specific protein kinase, geranyl and farnesyl pyrophosphate kinase, histidine protein kinase and 3'-5' exonuclease activities. Involved in cell proliferation, differentiation and development, signal transduction, G protein-coupled receptor endocytosis, and gene expression. Required for neural development including neural patterning and cell fate determination.[1] [2] [3] See AlsoReferences
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Categories: Homo sapiens | Large Structures | Han BG | Lee BI | Lee S | Min K