3t30

Structural highlights

Function

NPM2_HUMAN Core histones chaperone involved in chromatin reprogramming, specially during fertilization and early embryonic development. Probably involved in sperm DNA decondensation during fertilization.^[1]

See Also

• Nucleoplasmin

References

1. ↑ Platonova O, Akey IV, Head JF, Akey CW. Crystal Structure and Function of Human Nucleoplasmin (Npm2): A Histone Chaperone in Oocytes and Embryos. Biochemistry. 2011 Sep 20;50(37):8078-8089. Epub 2011 Aug 24. PMID:21863821 doi:10.1021/bi2006652