3tlx

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Crystal Structure of PF10_0086, adenylate kinase from plasmodium falciparum

Structural highlights

3tlx is a 4 chain structure with sequence from Plasmodium falciparum. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.75Å
Ligands:ADP, AMP, ATP, MG
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

KAD1_PLAF7 Catalyzes the reversible transfer of the terminal phosphate group between ATP and AMP (PubMed:15478799). Has very low activity with CTP, GTP, ITP and UTP and no activity with GMP, CMP, UMP or IMP in vitro (PubMed:15478799).[1]

See Also

References

  1. ↑ Ulschmid JK, Rahlfs S, Schirmer RH, Becker K. Adenylate kinase and GTP:AMP phosphotransferase of the malarial parasite Plasmodium falciparum. Central players in cellular energy metabolism. Mol Biochem Parasitol. 2004 Aug;136(2):211-20. PMID:15478799 doi:10.1016/j.molbiopara.2004.04.001

Contents


PDB ID 3tlx

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OCA

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