4gfu

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PTPN18 in complex with HER2-pY1248 phosphor-peptides

Structural highlights

4gfu is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2Å
Ligands:PTR
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PTN18_HUMAN Differentially dephosphorylate autophosphorylated tyrosine kinases which are known to be overexpressed in tumor tissues.

See Also

Contents


PDB ID 4gfu

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OCA

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