4oex

From Proteopedia

Jump to: navigation, search

Crystal structure of the PDE5A1 catalytic domain in complex with novel inhibitors

Structural highlights

4oex is a 1 chain structure with sequence from Homo sapiens. This structure supersedes the now removed PDB entry 3tse. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.14Å
Ligands:5EO, MG, ZN
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

PDE5A_HUMAN Plays a role in signal transduction by regulating the intracellular concentration of cyclic nucleotides. This phosphodiesterase catalyzes the specific hydrolysis of cGMP to 5'-GMP.

See Also

Contents


PDB ID 4oex

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://proteopedia.org/wiki/index.php/4oex"
Personal tools