4oj2

From Proteopedia

The structure of aquaporin

Structural highlights

4oj2 is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 3.05Å
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

AQP2_HUMAN Nephrogenic diabetes insipidus. The disease is caused by mutations affecting the gene represented in this entry.

Function

AQP2_HUMAN Forms a water-specific channel that provides the plasma membranes of renal collecting duct with high permeability to water, thereby permitting water to move in the direction of an osmotic gradient.

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PDB ID 4oj2

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Categories: Homo sapiens | Large Structures | Engel A | Lodowski D | Vahedi-Faridi A

4oj2

From Proteopedia

The structure of aquaporin

Structural highlights

Disease

Function

See Also

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