4pdc

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Crystal structure of Cowpox virus CPXV018 (OMCP) bound to human NKG2D

Structural highlights

4pdc is a 6 chain structure with sequence from Cowpox virus and Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.991Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

NKG2D_HUMAN Receptor for MICA, MICB, ULBP1, ULBP2, ULBP3 (ULBP2>ULBP1>ULBP3) and ULBP4. Plays a role as a receptor for the recognition of MHC class I HLA-E molecules by NK cells and some cytotoxic T-cells. Involved in the immune surveillance exerted by T- and B-lymphocytes.

See Also

Contents


PDB ID 4pdc

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OCA

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