Structural highlights
Function
ERG_META2 Reduces the C14=C15 double bond of 4,4-dimethyl-cholesta-8,14,24-trienol to produce 4,4-dimethyl-cholesta-8,24-dienol. Complements the deletion of the Delta(14)-sterol reductase gene ERG24 in yeast.[1]
References
- ↑ Li X, Roberti R, Blobel G. Structure of an integral membrane sterol reductase from Methylomicrobium alcaliphilum. Nature. 2014 Oct 12. doi: 10.1038/nature13797. PMID:25307054 doi:http://dx.doi.org/10.1038/nature13797