4x37

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Gallus interleukin-1 mutant - E118K

Structural highlights

4x37 is a 1 chain structure with sequence from Gallus gallus. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.63Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

O73909_CHICK Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells (By similarity).[RuleBase:RU003753]

See Also

Contents


PDB ID 4x37

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OCA

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