4xtk

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Structure of TM1797, a CAS1 protein from Thermotoga maritima

Structural highlights

4xtk is a 8 chain structure with sequence from Thermotoga maritima MSB8. This structure supersedes the now removed PDB entry 3lfx. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.7Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

CAS1_THEMA CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette (By similarity).

See Also

Contents


PDB ID 4xtk

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