5-hydroxytryptamine receptor 3D structures

From Proteopedia

3D structures of 5-hydroxytryptamine receptor

Updated on 28-August-2024 - For a general description of the protein see 5-hydroxytryptamine receptor

5-HT 1A

7e2z – hHT1A/ cytochrome b562 (mutant) + guanine nucleotide-binding protein – Cryo EM

7e2y – hHT1A/ cytochrome b562 (mutant) + guanine nucleotide-binding protein + serotonin– Cryo EM

8fy8, 8fye, 8fyl, 8fyx – hHT1A/ cytochrome b562 (mutant) + guanine nucleotide-binding protein + drug – Cryo EM

8fyt – hHT1A/ cytochrome b562 (mutant) + guanine nucleotide-binding protein + LSD + cholesterol – Cryo EM

8pjk – hHT1A + guanine nucleotide-binding protein + inositol derivative + cholesterol – Cryo EM

8jsp, 8pkm – hHT61A+ guanine nucleotide-binding protein + scFv + drug – Cryo EM

5-HT 1B

4iaq, 4iar, 5v54 – hHT1B/cytochrome b562 (mutant) + drug - human

7c61 – hHT1B/cytochrome b562 (mutant) + antibody

6g79 – hHT1B + guanine nucleotide-binding protein

5-HT 1D

7e32 – hHT1D + guanine nucleotide-binding protein + Scfv + serotonin – Cryo EM

5-HT 1E

8ugy, 8uh3 – hHT1E + guanine nucleotide-binding protein + drug – Cryo EM

5-HT 1F

7exd – hHT1F + guanine nucleotide-binding protein + Scfv + drug – Cryo EM

5-HT 2A

6a93, 6a94, 7vod, 7voe, 7wc5, 7wc7, 7wc8, 7wc9, 8jt8 – hHT2A/cytochrome b562 (mutant) + drug

7wc4 – hHT2A/cytochrome b562 (mutant) + serotonin

7wc6 – hHT2A/cytochrome b562 (mutant) + LSD

6wgt – hHT2A/cytochrome b562 + hallucinogen

6wh4 – hHT2A/cytochrome b562 + agonist

7ran, 8v6u – hHT2A + guanine nucleotide-binding protein + Scfv + agonist – Cryo EM

8uwl – hHT2A + guanine nucleotide-binding protein + Scfv + drug – Cryo EM

5-HT 2B

4nc3 – hHT2B/cytochrome b562 (mutant)

4ib4 – hHT2B/cytochrome b562 (mutant) + drug

7srq – hHT2B + LSD – Cryo EM

7srs – hHT2B + arrestin + antibody + LSD – Cryo EM

[7srrl]] – hHT2B + guanine nucleotide-binding protein + Scfv + LSD – Cryo EM

5tvn – hHT2B/cytochrome b562 (mutant) + LSD

5tud – hHT2B/cytochrome b562 (mutant) + antibody

6drx, 6dry, 6drz, 6ds0 – hHT2B/cytochrome b562 + agonist + cholesterol

5-HT 2C

6bqg, 6bqh – hHT2C/cytochrome b562 (mutant) + ergotamine

8dpf, 8dph, 8dpi – hHT2C + guanine nucleotide-binding protein + scFv + drug – Cryo EM

8dpg – hHT2C + guanine nucleotide-binding protein + scFv + serotonin derivative – Cryo EM

5-HT 3A

8axd – hHT3A – Cryo EM

8bla, 8blb – hHT3A + drug – Cryo EM

4pir – mHT3A + VHH15 - mouse

6be1, 8bl8, 8c1w, 8c1z, 8c20, 8c21 – mHT3A – Cryo EM

6his – mHT3A + drug

6np0, 6w1j, 6w1m, 6w1y, 6y1z, 8aw2 – mHT3A + drug – Cryo EM

8cc6, 8cc7 – mHT3A + inhibitor – Cryo EM

6dg7, 6dg8, 6hin, 6hio, 6hiq, 8frz, 8fsb – mHT3A + serotonin – Cryo EM

6y59, 6y5a, 6y5b – mHT3A (mutant) + serotonin – Cryo EM

8frx, 8frw, 8fsp, 8fsz – mHT3A + agonist – Cryo EM

5-HT 4

7xt9, 7xta – hHT4 + guanine nucleotide-binding protein + serotonin – Cryo EM

7xt8 – hHT4 + guanine nucleotide-binding protein + nanobody + serotonin – Cryo EM

5-HT 5A

7um5, 7um6, 7um7 – hHT5A + minigo + guanine nucleotide-binding protein + scFv + drug – Cryo EM

7um4 – hHT5A + PGS + quinolone derivative

5-HT 6

7xtb – hHT6 + guanine nucleotide-binding protein + nanobody + serotonin – Cryo EM

8jlz – hHT6 + guanine nucleotide-binding protein + nanobody + agonist – Cryo EM

7ys6 – hHT6 + guanine nucleotide-binding protein + scFv + serotonin – Cryo EM