Structural highlights
Publication Abstract from PubMed
The 1.25 A resolution H32:R crystal structure of a 20 nt ribonucleotide that binds to the TREX-2 complex with high affinity shows a double-stranded RNA duplex arranged along a crystallographic 31 axis in which the antiparallel chains overlap by 18 nucleotides and are related by a crystallographic twofold axis. The duplex shows C-A, U-U and C-C noncanonical base pairings together with canonical Watson-Crick A-U and G-C pairs and a G-U wobble.
1.25 A resolution structure of an RNA 20-mer that binds to the TREX2 complex.,Valkov E, Stewart M Acta Crystallogr F Struct Biol Commun. 2015 Oct 1;71(Pt 10):1318-21. doi:, 10.1107/S2053230X1501643X. Epub 2015 Sep 23. PMID:26457524[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Valkov E, Stewart M. 1.25 A resolution structure of an RNA 20-mer that binds to the TREX2 complex. Acta Crystallogr F Struct Biol Commun. 2015 Oct 1;71(Pt 10):1318-21. doi:, 10.1107/S2053230X1501643X. Epub 2015 Sep 23. PMID:26457524 doi:http://dx.doi.org/10.1107/S2053230X1501643X