5do7

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Crystal Structure of the Human Sterol Transporter ABCG5/ABCG8

Structural highlights

5do7 is a 4 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 3.93Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Disease

ABCG5_HUMAN Sitosterolemia. The disease is caused by mutations affecting the gene represented in this entry.

Function

ABCG5_HUMAN Transporter that appears to play an indispensable role in the selective transport of the dietary cholesterol in and out of the enterocytes and in the selective sterol excretion by the liver into bile.

See Also

Contents


PDB ID 5do7

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OCA

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