5h4y

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Crystal structure of human synaptotagmin 5 C2A domain

Structural highlights

5h4y is a 1 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.9Å
Ligands:ACT, CA
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SYT5_HUMAN May be involved in Ca(2+)-dependent exocytosis of secretory vesicles through Ca(2+) and phospholipid binding to the C2 domain or may serve as Ca(2+) sensors in the process of vesicular trafficking and exocytosis. Regulates the Ca(2+)-dependent secretion of norepinephrine in PC12 cells. Required for export from the endocytic recycling compartment to the cell surface (By similarity).

See Also

Contents


PDB ID 5h4y

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OCA

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