5m9o

From Proteopedia

Crystal structure of human SND1 extended Tudor domain in complex with a symmetrically dimethylated E2F peptide

Structural highlights

5m9o is a 2 chain structure with sequence from Homo sapiens. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:	X-ray diffraction, Resolution 1.45Å
Ligands:	2MR
Resources:	FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

SND1_HUMAN Functions as a bridging factor between STAT6 and the basal transcription factor. Plays a role in PIM1 regulation of MYB activity. Functions as a transcriptional coactivator for the Epstein-Barr virus nuclear antigen 2 (EBNA2).^[1]

References

↑ Tong X, Drapkin R, Yalamanchili R, Mosialos G, Kieff E. The Epstein-Barr virus nuclear protein 2 acidic domain forms a complex with a novel cellular coactivator that can interact with TFIIE. Mol Cell Biol. 1995 Sep;15(9):4735-44. PMID:7651391

1 Structural highlights
2 Function
3 References

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PDB ID 5m9o

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5m9o

From Proteopedia

Crystal structure of human SND1 extended Tudor domain in complex with a symmetrically dimethylated E2F peptide

Structural highlights

Function

References

Contents

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