Structural highlights
Function
Q97ZH2_SACS2
Publication Abstract from PubMed
Domain of unknown function 61 (DUF61) family proteins widely exist in archaea and the genes of DUF61 proteins in crenarchaea are in an operon containing two genes of box C/D RNA protein complexes. Here we report the solution NMR structure of DUF61 family member protein SSO0941, from the hyperthermophilic archaeon Sulfolobus solfataricus. SSO0941 has a rigid core structure and flexible N- and C-terminal regions as well as a negatively-charged independent C-terminal helix. The core structure consists of N- and C-terminal subdomains, in which the C-terminal subdomain shows significant structural similarity with several nucleic acid binding proteins. The structure of SSO0941 is the first representative structure of DUF61 family proteins.
Solution structure of an archaeal DUF61 family protein SSO0941 encoded by a gene in the operon of box C/D RNA protein complexes.,Zhou T, Yao X, Wang J, Feng Y J Struct Biol. 2018 Mar 8. pii: S1047-8477(18)30065-0. doi:, 10.1016/j.jsb.2018.03.003. PMID:29526782[1]
From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.
References
- ↑ Zhou T, Yao X, Wang J, Feng Y. Solution structure of an archaeal DUF61 family protein SSO0941 encoded by a gene in the operon of box C/D RNA protein complexes. J Struct Biol. 2018 Mar 8. pii: S1047-8477(18)30065-0. doi:, 10.1016/j.jsb.2018.03.003. PMID:29526782 doi:http://dx.doi.org/10.1016/j.jsb.2018.03.003
