Structural highlights
6byx is a 2 chain structure with sequence from Alteromonas sp. LOR. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
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| Method: | X-ray diffraction, Resolution 2.208Å |
| Ligands: | , , , , , |
| Resources: | FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT |
Function
UL24S_ALTSL Ulvan lyase involved in ulvan degradation. Ulvan is the main polysaccharide component of the Ulvales (green seaweed) cell wall. It is composed of disaccharide building blocks comprising 3-sulfated rhamnose (Rha3S) linked to D-glucuronic acid (GlcA), L-iduronic acid (IduA), or D-xylose (Xyl). Ulvan lyase catalyzes preferentially the endolytic cleavage of the glycosidic bond between Rha3S and the uronic acid GlcA, but not IduA, producing oligosaccharides that have unsaturated 4-deoxy-L-threo-hex-4-enopyranosiduronic acid (deltaUA) at the non-reducing end. The most abundant end products in the degradation of the ulvan polysaccharide were deltaUA-Rha3S disaccharides and deltaUA-Rha3S-IduA-Rha3S and deltaUA-Rha3S-Xyl-Rha3S tetrasaccharides.[1]
References
- ↑ Kopel M, Helbert W, Belnik Y, Buravenkov V, Herman A, Banin E. New Family of Ulvan Lyases Identified in Three Isolates from the Alteromonadales Order. J Biol Chem. 2016 Mar 11;291(11):5871-5878. PMID:26763234 doi:10.1074/jbc.M115.673947
