6ko2 | pdb_00006ko2
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Crystal Structure of BRD4-Brmo2 in complex with H2A.ZK4acK7ac peptide
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Structural highlights
DiseaseBRD4_HUMAN Note=A chromosomal aberration involving BRD4 is found in a rare, aggressive, and lethal carcinoma arising in midline organs of young people. Translocation t(15;19)(q14;p13) with NUT which produces a BRD4-NUT fusion protein.[1] [2] FunctionBRD4_HUMAN Plays a role in a process governing chromosomal dynamics during mitosis (By similarity). See AlsoReferences
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This page was last modified 10:28, 15 November 2023.