6l8x

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Crystal structure of Siraitia grosvenorii ugt transferase mutant2

Structural highlights

6l8x is a 1 chain structure with sequence from Siraitia grosvenorii. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 1.55Å
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

74AC1_SIRGR Catalyzes the transfer of a glucose moiety to the C-3 hydroxyl of mogrol to form mogroside IE (PubMed:25759326, Ref.3). Besides mogrol, UGT74AC1 also shows activity in vitro with quercetin and naringenin as substrate (PubMed:25759326).[1] [2]

See Also

References

  1. ↑ Dai L, Liu C, Zhu Y, Zhang J, Men Y, Zeng Y, Sun Y. Functional Characterization of Cucurbitadienol Synthase and Triterpene Glycosyltransferase Involved in Biosynthesis of Mogrosides from Siraitia grosvenorii. Plant Cell Physiol. 2015 Jun;56(6):1172-82. PMID:25759326 doi:10.1093/pcp/pcv043
  2. ↑ Dai L, Liu C, Zhu Y, Zhang J, Men Y, Zeng Y, Sun Y. Functional Characterization of Cucurbitadienol Synthase and Triterpene Glycosyltransferase Involved in Biosynthesis of Mogrosides from Siraitia grosvenorii. Plant Cell Physiol. 2015 Jun;56(6):1172-82. PMID:25759326 doi:10.1093/pcp/pcv043

Contents


PDB ID 6l8x

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OCA

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