6lsm

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Tubulin Polymerization Inhibitors

Structural highlights

6lsm is a 6 chain structure with sequence from Gallus gallus, Mus musculus and Sus scrofa. Full crystallographic information is available from OCA. For a guided tour on the structure components use FirstGlance.
Method:X-ray diffraction, Resolution 2.751Å
Ligands:ACP, CA, CL, ERX, GDP, GTP, MES, MG
Resources:FirstGlance, OCA, PDBe, RCSB, PDBsum, ProSAT

Function

TBB_PIG Tubulin is the major constituent of microtubules. It binds two moles of GTP, one at an exchangeable site on the beta chain and one at a non-exchangeable site on the alpha chain.

Contents


PDB ID 6lsm

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OCA

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